Sat Mar 04 2023

40 articles - From Saturday Feb 25 2023 to Saturday Mar 04 2023

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Guidelines

Guidelines and related publications, position statements, white papers, technical reviews, consensus statements, etc…


Meta-analysis

meta-analyses and systematic reviews

Am J Clin Nutr

Important food sources of fructose-containing sugars and adiposity: A systematic review and meta-analysis of controlled feeding trials.

Energy control and food sources mediate the effect of fructose-containing sugars on adiposity. The evidence provides a good indication that excess energy from sugars (particularly SSBs at high doses =20%E or 100 g/d) increase adiposity, whereas their removal decrease adiposity. Most other food sources had no effect, with some showing decreases (particularly fruits at lower doses =10%E or 50 g/d).

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J Crohns Colitis

Tofacitinib for acute severe ulcerative colitis: a systematic review.

Tofacitinib appears promising for treatment of ASUC with high short-term colectomy-free survival among refractory patients otherwise deemed for colectomy. However, large high-quality studies are needed.

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Liver Transpl

Systematic review and meta-analysis of open versus laparoscopy-assisted versus pure laparoscopic versus robotic living donor hepatectomy.

There seems to be a marginal benefit in EBL and/or LOS in favor of PLLDH and RLDH. The complexity of these procedures limits them to transplant centers with high volume and experience. Future studies should investigate self-reported donor experience and the associated economic costs of these approaches.

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Original articles

RCT, clinical trials, retrospective studies, etc…

Am J Clin Nutr

A linear programming based method for designing menus for controlled feeding trials.

The model helps to design menus in a fast, objective, transparent, and reproducible way. It greatly facilitates the design procedure for menus in controlled feeding trials and lowers development costs.

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A Multi-Meal Paradigm producing a low glycemic response is associated with modest cognitive benefits relative to a high glycemic response: A randomized, crossover trial in Type 2 Diabetes patients.

This study shows that a multi-meal paradigm producing a low glycemic response was associated with some benefits for cognitive function in patients with T2DM. Clinical trail registry reference NCT03360604 (clinical trial.gov).

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Adherence to the EAT-Lancet diet and risk of coronary events in the Malmo Diet and Cancer cohort study.

Our data indicate that adherence to the EAT-Lancet diet was associated with a lower risk of coronary events.

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An assessment of the impact of cross-cultural variation in plant macronutrients on the recommendations of the Paleo Diet.

The estimated whole-diet macronutrient percentages that form the basis of the Paleo Diet's macronutrient recommendations are not robust. Using plant data from multiple regions leads to significantly different estimates. Additionally, the macronutrient ranges derived from our whole-diet macronutrient percentages overlap with those recommended by the US Department of Agriculture and the WHO. This undercuts one of the main justifications for adopting the Paleo Diet-namely that because it is vastly different from Western diets, it can reduce the probability of experiencing noncommunicable diseases. There may still be reasons for adopting the Paleo Diet rather than a conventional diet, but healthier macronutrient percentages is not one of them.

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Association between blood N-3 fatty acid levels and the risk of coronavirus disease 2019 in the UK Biobank.

These findings suggest that nutritional strategies to increase the circulating n-3 PUFA levels, such as increased consumption of oily fish and/or use of n-3 FA supplements, may reduce the risk of adverse COVID-19 outcomes.

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Digestive and metabolic bioavailability in healthy humans of 15N-labeled rapeseed and flaxseed protein incorporated in biscuits.

Despite good digestibility, flaxseed protein cooked in biscuits was penalized by both lysine insufficiency and poor lysine digestibility that decreased its DIAAS and increased deamination. By contrast, rapeseed was moderately digestible but presented no limiting IAA, resulting in an excellent DIAAS and low deamination. This study was registered at clinicaltrials.gov as NCT04024605.

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Low calf circumference adjusted for body mass index is associated with prolonged hospital stay.

BMI-adjusted low CC was identified in more than 60% of hospitalized patients and was an independent predictor of longer LOS.

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Nutrient-sensitive approach for sustainability assessment of Australian macronutrient dietary recommendations.

We conclude that encouraging consumers to adhere to the lower limit of the recommended intake of proteins and meeting the protein requirement through protein-dense plant sources could improve dietary environmental and economic sustainability in Australia. Our findings provide a means of understanding the sustainability of dietary recommendations concerning macronutrients for any country where input-output databases are available.

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Plant-based diets and the risk of pancreatic cancer: a large prospective multicenter study.

In this US population, adherence to a healthy plant-based diet confers a lower risk of pancreatic cancer, whereas adherence to a less healthy plant-based diet confers a higher risk. These findings highlight the importance of considering plant food quality in preventing pancreatic cancer.

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The effect of modest changes in sleep on dietary intake and eating behavior in children: secondary outcomes of a randomized crossover trial.

Mild sleep deprivation may play a role in pediatric obesity by increasing caloric intake, particularly from noncore and ultraprocessed foods. Eating in response to emotions rather than perceived hunger may partly explain why children engage in unhealthy dietary behaviors when tired.

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Weight gain in pregnancy and infant birthweight after the onset of the COVID-19 pandemic: an interrupted time series analysis.

We observed a modest increase in weight gain after the onset of the pandemic among pregnant people but no changes in infant birthweights. This weight change could be more important in high BMI subgroups.

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J Crohns Colitis

Mercaptopurine for the treatment of ulcerative colitis - a randomised placebo-controlled trial.

Optimised mercaptopurine treatment was superior to placebo in achieving clinical, endoscopic and histological outcomes at one year following corticosteroid induction treatment in UC patients. More adverse events occurred in the mercaptopurine group.

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Should we target complete endoscopic healing in patients with acute severe ulcerative colitis?

In a cohort of patients admitted for ASUC in whom clinical and endoscopic healing has been achieved with a second-line medical therapy, better survival without disease relapse was observed with complete endoscopic healing.

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Liver Transpl

Autoimmune hepatitis presenting as acute liver failure. A 20-year retrospective review of North America.

Acute liver failure secondary to autoimmune hepatitis is associated with a high short-term mortality. We developed a model specifically for autoimmune hepatitis that may be helpful in predicting 21-day transplant-free survival and early identification of patients in need for expedited liver transplant evaluation.

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Cardiac index and hepatopulmonary syndrome in liver transplantation candidates: The Pulmonary Vascular Complications of Liver Disease Study.

HPS was associated with higher CI among LT candidates. Independent of HPS, higher CI was associated with increased dyspnea and worse functional class, QOL, and arterial oxygenation.

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Evaluating the outcomes of donor-recipient age differences in young adults undergoing liver transplantation.

In younger patients who are not in emergent need of a transplant, preferential allocation of younger aged donor offers would optimize organ utility by increasing postoperative graft survival time.

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Hepatic venous reconstruction of the left lateral segment with emphasis on anomalous hepatic vein in pediatric liver transplantation.

There was no statistically significant difference in the posttransplant outcomes between the graft types. The venous reconstruction of the AHV with HVG interposition had similar outcomes in the short and long-term.

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Initial outcome of external biliary drainage in living donor liver transplantation with pure laparoscopic donor hepatectomy.

However, efforts should be made to prevent EBD-related complications. Further studies are needed to establish appropriate selection criteria for EBD.

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Outcomes of sexagenarian living liver donors in Korea: A multicenter study.

Present study suggests that highly selected elderly living donors (=60 y) can safely donate with similar recipient graft survival rates though the recipient overall patient survival is inferior compared to the 50s donor group.

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Saroglitazar improves nonalcoholic fatty liver disease and metabolic health in liver transplant recipients.

The study provides preliminary data demonstrating safety and metabolic benefits of saroglitazar in LT recipients and underscore the importance of future studies to establish its efficacy post-LT.

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Pancreatology

Prognostic value of major pathological response following neoadjuvant therapy for non resectable pancreatic ductal adenocarcinoma.

Patients experienced a major pathological response after neoadjuvant treatment have an increased survival, and major pathologic response is an independent predictor of OS. A normal CA19-9 value and radiological tumor size at restaging are confirmed to be independent predictors of major pathologic response.

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Reviews&Editorials

Plenty of the editorials are available as full text through the publisher website using the provided link

Am J Clin Nutr

Bioactive omega-3 fatty acids are associated with reduced risk and severity of SARS-CoV-2 infection.

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Delaying children's bedtime affects food intake and is related to emotions rather than satiety.

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Fructose sources have an unequal impact on adiposity-are we surprised?

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Let's do the math: embracing mathematical modeling to advance nutrition research.

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Pancreatic cancer: Are all plant-based diets the same?

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Quasi-experimental study designs can inform pandemic effects on nutrition and weight gain in pregnancy.

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Inflamm Bowel Dis

Coronary Artery Plaque Assessment by CT Angiogram in Inflammatory Bowel Disease.

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J Crohns Colitis

Going Beyond a Treat-To-Target to a Treat-To-Clear and a Treat-To-Trough Therapeutic Strategy in Patients with Inflammatory Bowel Disease?

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Miscellaneous

misc publications eg case reports, tools of the trade, images of the month, etc…

Inflamm Bowel Dis

Automated Clinical Pathway Utilizing Custom Risk Stratification Identifies Substantial Rates of Overdue Follow-up Among Patients With Inflammatory Bowel Disease and Facilitates Population Health Interventions.

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Plant-Based Diet Recommended for Inflammatory Bowel Disease.

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Reply: Plant-Based Diet Recommended for Inflammatory Bowel Disease.

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Liver Transpl

Evaluation of the transplantation of ACLF grade 3 model (TAM) in the multicenter French experience.

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Letter to the Editor Regarding: Viability assessment and transplantation of fatty liver grafts using end-ischemic normothermic machine perfusion.

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Post-liver transplant acute cardiomyopathy: role of prospective cardiac evaluation in immediate post-transplant period.

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Reply: Viability assessment and transplantation of fatty liver grafts using end-ischemic normothermic machine perfusion.

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Short- and long-term outcomes of donor and recipient in living donor liver transplantation using variant grafts.

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Letters&Replies

Letters to the editors and authors’ replies